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“Someone is trying to jump off a bridge and they give him ketamine in the ambulance to calm him down and 9 months later, he says, ‘I haven’t felt suicidal for 9 months.’ “When enough stories like that started to pile up, doctors said, ‘Maybe there’s something here,’” says Stewart, an emergency physician and founder of Insight Ketamine in Santa Fe, NM. Like the drug itself, Stewart got his start in combat medicine during the Vietnam War. Some doctors also use ketamine to treat suicidal thoughts.
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Aspirin is used to treat mild to moderate pain, and to reduce inflammation and fever. Low doses (eg 75mg, known as mini-aspirin), are used to thin the blood and reduce the risk of unwanted blood clots. Aspirin works by inhibiting two enzymes (COX-1 and COX-2) that generate substances (prostaglandins, thromboxanes) which stimulate pain receptors to trigger sensations of pain. COX-1 is mainly active in the gastrointestinal tract and is needed to maintain the protective mucus coating of the stomach. COX-2 on the other hand is active at sites of inflammation. Aspirin is used to relieve pain associated with fever, pain plus inflammation and swelling (eg sprained ankle), headache, migraine, period pains, muscular aches and dental pain. Dose: A typical dose is 300mg – 600mg aspirin after meals, at intervals of at least four hours. Always follow instructions on the label as different products vary.
Prescribing tramadol to minimise adverse effects. The usual dose of tramadol is 50–100 mg per dose, with a maximum daily dose of 400 mg, and at least four hours between doses.5 Older patients are most at risk of developing tramadol-related adverse effects, in which case the maximum daily dose should be reduced to 300 mg.5 In patients with hepatic or renal dysfunction, who may have reduced elimination of tramadol, a low starting dose of immediate-release tramadol, e.g. 50 mg, with titration to effect and 12-hour dosing is appropriate;3,4 modified-release tramadol should be avoided in these patients.5 Tramadol should be avoided in patients with severe renal dysfunction, i.e. a creatinine clearance < 10 mL/minute. If patients experience nausea with the use of tramadol, consider lowering the dose and concurrently using paracetamol (see below) or switch the patient to codeine, dihydrocodeine or a NSAID. Modified-release tramadol may be associated with fewer adverse effects in some patients.
Medication helped more in some areas than others. Parents in our survey said medication helped equally—and most of all—with academic performance (very helpful for 35 percent) and behavior at school (very helpful for 35 percent). It also helped well with behavior at home (very helpful for 26 percent), and fairly well with social relationships (very helpful for 19 percent) and self-esteem (very helpful for 18 percent). Furthermore, the degree of helpfulness with academic performance, behavior at school, and behavior at home most likely accounted for how helpful the parents rated medication as a specific strategy. Medication seems to lessen some ADHD symptoms, but behavioral strategies can help manage the condition for the long-term. Children taking either stimulants or nonstimulants who started off with serious symptoms showed the most change, with a greater likelihood of improvement. (Kids whose symptoms started off mild also improved, but the difference wasn't as great.) Amphetamines and methylphenidates were equally associated with symptom changes in all areas (See more about ADHD symptoms.)
Over-the-counter sleep aids: Most of these sleeping pills are antihistamines. There is no proof that they work well for insomnia, and they can cause some drowsiness the next day. They're safe enough to be sold without a prescription. But if you're taking other drugs that also contain antihistamines — like cold or allergy medications — you could inadvertently take too much.
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